Table 4 Characteristics of the drugs sorted by patent challenges
From: Patenting and patent challenges in South Korea after introducing a patent linkage system
Non-challenged | Challenged | % of challenged | P-value | |
|---|---|---|---|---|
Number of drugs (N) | 481 | 94 | (16%) | |
Drug type | < 0.0001 | |||
Chemical | 396 | 93 | (19%) | |
Biologic | 85 | 1 | (1%) | |
Statutory exclusivity | < 0.0001 | |||
No | 223 | 21 | (9%) | |
Yes | 258 | 73 | (22%) | |
Manufacturer type | 0.0010 | |||
Domestic | 185 | 19 | (9%) | |
Foreign | 296 | 75 | (20%) | |
Administration | < 0.0001 | |||
Oral | 305 | 82 | (21%) | |
Injection | 124 | 4 | (3%) | |
Others | 52 | 8 | (13%) | |
ATC classification | 0.0025 | |||
J/L | 154 | 13 | (8%) | |
A/B/C | 184 | 51 | (22%) | |
M/N | 65 | 12 | (16%) | |
Others | 78 | 18 | (19%) | |
Year | < 0.0001 | |||
2012 | 44 | 24 | (35%) | |
2013 | 82 | 18 | (18%) | |
2014 | 82 | 25 | (23%) | |
2015 | 98 | 14 | (13%) | |
2016 | 92 | 7 | (7%) | |
2017 | 83 | 6 | (7%) | |
Patents | 1.79 | 2.34 | 0.0042 | |
Market size | 413,749 | 466,502 | 0.1136 | |
Number of manufacturers | 379 | 395 | 0.5841 |