Table 3 Meta-analysis results

CVA

symptoms onset to ED door time

21

98.31%

DoM = 15.67 min, 95% CI:-22.84 to 54.18

0.4252

rt-PA administration

25

97.56%

RR = −0.11, 95% CI:-0.33 to 0.11

0.0914

ACS

symptom onset to first medical contact^a

12

99.52%

DoM = 65.71 min, 95% CI:-11.55 to 142.98

0.0955

symptom onset to administration

8

61.21%

DoM = 30.94 min, 95% CI:12.919 to 48.966

0.0008

aneurismal SAH

Vassospasm finding on CT angiography

2

0.0%

RR = 1.575, 95% CI:0.72 to 2.42

0.003

Fisher grade > 2

2

0.0%

RR = -0.0064, 95% CI: −0.2196 to 0.2068

0.9533

WFNS > 3

2

42.40%

RR = + 0.3088, 95% CI:-0.2631 0.8807

0.2899

Acute appendicitis

Perforated appendicitis

20

18.59%

RR = + 0.362, 95% CI:0.2549 to 0.4690

<.0001

later than 72 hours ED visit

3

75.32%

RR = + 0.641, 95% CI:-0.6104 to 1.8938

0.315

ectopic pregnancy

Rupture of ectopic pregnancy

8

56.20%

RR = + 0.112, 95% CI:0.0248 to 0.201

trim and filled: RR = + 0.0670, 95% CI: −0.0064 to 0.1404

trim and filled: 0.0734

newly diagnosed T1DM

DKA presentation

8

49.37%

RR = + 0.224, 95% CI:0.062 to 0.38

0.0065

Testicular Torsion

Orchiectomy

6

3%

RR = + 0.259, 95% CI:0.026 to 0.492

0.029